Although many current treatments can improve vision in keratoconus, they do not treat the underlying cause of the corneal weakness and distortion ie they do not stop the progression of keratoconus. Collagen Cross Linking with riboflavin (commonly known as C3R) is one such treatment modality which stops progressive weakening of the cornea that occurs in keratoconus.

The one hour C3-R treatment is performed in the hospital. During the treatment, custom-made riboflavin eye drops are applied to the cornea, which is then activated by ultraviolet A light(370nm). This amazingly simple process has been shown in laboratory and clinical studies to increase the amount of collagen cross-linking in the cornea and strengthen the cornea. In published European studies, such treatments were proven safe and effective in patients.